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will not lock; but because they use the same send-receive system, once they have both sent information, they will both return to the wait state, expecting a response A better solution to the problem is to use a protocol that places rules and restrictions on the communication method and order This is how Simple Mail Transfer Protocol (SMTP) and similar protocols work The client sends a command to the server, and the immediate response from the server tells the client what to do next The response may include data and will definitely include an end-of-data string In effect, it s similar to the technique used when communicating by radio At the end of each communication, you say Over to indicate to the recipient that you have finished speaking In essence, it still uses the same best-guess method for communication Providing the communication starts off correctly, and each end sends the end-ofcommunication signal, the communication should continue correctly Although generally thought of as a technique for communicating between two different machines, you can also use sockets to communicate between two processes on the same machine This can be useful for two reasons First of all, communicating between processes on a single machine (IPC interprocess communication) allows you to control and cooperatively operate several different processes Most servers use IPC to manage a number of processes that support a particular service We ll be looking at the general techniques available for networking between processes, either on the machine or across a network to a different machine Techniques include those using the built-in Perl functions and those using modules available from CPAN that simplify the process for communicating with existing protocol standards If you want more information on networking with sockets and streams under TCP, UDP, and IP, then I can recommend The UNIX System V Release 4 Programmers Guide: Networking Interfaces (1990, Englewood Cliffs, NJ: Prentice Hall), which covers the principles behind networking, as well as the C source code required to make it work.

con uent white matter lesions A brain biopsy revealed amebae that could have been easily mistaken for macrophages or cellular debris; the organism proved to be Balamuthia (Katz et al) Treatment with the usual antiprotozoal agents is largely ineffective Because of the in vitro sensitivity of Naegleria to amphotericin B, this drug should be used by the same schedule as for cryptococcal meningitis With such a regimen in combination with rifampin, recovery is sometimes possible Malaria A number of other protozoal diseases are of great importance in tropical regions One is cerebral malaria, which complicates about 2 percent of cases of falciparum malaria This is a rapidly fatal disease characterized by headache, seizures, and coma, with diffuse cerebral edema and only very rarely by focal features such as hemiplegia, aphasia, hemianopia, or cerebellar ataxia Cerebral capillaries and venules are packed with parasitized erythrocytes and the brain is dotted with small foci of necrosis surrounded by glia (Durck nodes) These ndings have been the basis of several hypotheses (one of which attributes the cerebral symptoms to mechanical obstruction of the vessels), but none is entirely satisfactory Also, it seems unlikely that a disorder of immune mechanisms is directly involved in the pathogenesis (see reviews by Newton et al and by Turner for a discussion of current hypotheses) Usually the neurologic symptoms appear in the second or third week of the infection, but they may be the initial manifestation Children in hyperendemic regions are the ones most susceptible to cerebral malaria Among adults, only pregnant women and nonimmune individuals who discontinue prophylactic medication are liable to CNS involvement (Toro and Roman) Useful laboratory ndings are anemia and parasitized red blood cells The CSF may be under increased pressure and sometimes contains a few white blood cells, and the glucose content is normal With Plasmodium vivax infections, there may be drowsiness, confusion, and seizures without invasion of the brain by the parasite Treatment Quinine, chloroquine, and related drugs are curative if the cerebral symptoms are not pronounced, but once coma and convulsions supervene, 20 to 30 percent of patients do not survive It has been stated that that the administration of large doses of dexamethasone, given as soon as cerebral symptoms appear, may be lifesaving, but most studies including those of our colleagues have expressed the view that corticosteroids are ineffective Exchange transfusions may confer a small bene t on survival in severe cases Trypanosomiasis This is a common disease in equatorial Africa and in Central and South America The African type ( sleeping sickness ) is caused by Trypanosoma brucei and is transmitted by several species of the tsetse y There has been an alarming increase in this disease in sub-Saharan Africa during the last two decades The infection begins with a chancre at the site of inoculation and localized lymphadenopathy Posterior cervical adenopathy is highly characteristic of CNS infection (Winterbottom sign); another sign of neurologic interest is pronounced pain at sites of minor injury (called Kerandel hyperesthesia) Later, episodes of parasitemia occur, and at some time during this stage of dissemination, usually in the second year of the infection, the trypanosomes give rise to a diffuse meningoencephalitis The latter expresses itself clinically as a chronic progressive neurologic syndrome consisting of a reversal or disruption of circadian sleep rhythm, vacant facial expression, and in some, ptosis and ophthalmoplegia, dysarthria, and then muteness, seizures, progressive apathy, stupor, and coma.

The first stage in making a network connection is to get the information you need about the host you are connecting to You will also need to resolve the service port and protocol information before you start the communication process Like other parts of the networking process, all of this information is required in numerical rather than name format You therefore need to be able to resolve the individual names into corresponding numbers This operation is supported by several built-in functions, which are described in the sections that follow, divided into their different types (Hosts, Protocols, Services, Networks, and so on)

The South American variety of trypanosomiasis (Chagas disease) is caused by Trypanosoma cruzi and is transmitted from infected animals to humans by the bite of reduviid bugs The sequence of local lymphadenopathy, hematogenous dissemination, and chronic meningoencephalitis is like that of African trypanosomiasis Serologic tests are available to con rm the diagnosis Treatment Treatment is with pentavalent arsenicals, mainly melarsoprol, which are more effective in the African than in the South American form of the disease An encephalopathy occurs in one fth of cases during the institution of treatment Unusually high rates of relapse are being reported after treatment A thorough review of the subject of trypanosomiasis is given by Barrett and colleagues They also discuss the important topic of vector control