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As you saw in the previous section, a rather lengthy C# script helped pull together an ASPNET application with LINQ structures It was able to access data from a database However, besides a database, LINQ can be used with virtually any kind of data source In this next example, you will see how to use LINQ to access data in a simple array

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with the chronic use of disul ram in the treatment of alcoholism Its neurotoxic effects have been attributed to the action of carbon disul de, which is produced during the metabolism of the drug, and is known to cause polyneuropathy and sometimes an optic neuropathy in workers in the viscose rayon industry Pathologic data, though scant, tend to discredit this notion, insofar as disul ram evokes a wallerian type of axonal degeneration, whereas carbon disul de neuropathy is characterized by swollen (giant) axons that are lled with neuro laments (Bouldin et al) Other Pharmaceutical Agents Causing Polyneuropathy Some patients who have taken phenytoin for decades may show an absence of ankle and patellar re exes, a mild distal symmetrical impairment of sensation, reduced conduction velocity in the peripheral nerves of the legs, and, rarely, weakness of the distal musculature The mechanism and frequency of this complication are not clear The cholesterol lowering statin drugs have been implicated in a painful, paresthetic distal axonal polyneuropathy, often, it has been stated, with retained re exes (Geist et al) More often the problem with statins is one of a toxic myopathy The frequency of polyneuropathy is very low but, if no other explanation is identi ed, it may be advisable to discontinue the drug Colchicine has long been known to cause a myopathy, but a few cases of predominantly axonal sensory neuropathy have also been reported Thalidomide, which can produce sensory polyneuropathy, had been withdrawn from the market but is now being used again experimentally for graft-versus-host disease and for drug-resistant erythema nodosum, leprous eruptions, and apthous stomatitis, particularly in AIDS patients also as an experimental antineoplastic agent for vascular tumors The thalidomide polyneuropathy is dosedependent and can be anticipated at certain levels of administration Severe botulinum poisoning and the prolonged use of neuromuscular blocking agents is said to leave some patients with a distal axonopathy, but this must be rare Residual effects of polyneuropathy were seen in patients with the toxic eosinophilia-myalgia syndrome; the problem was traced to the ingestion of adulterated L-tryptophan which had been used in nonprescription drugs for insomnia (page 1211) One patient under our care suffered permanent are exic quadriplegia There may be an eosinophilic in ltrate in nerves, but the neuropathy is probably the result of a direct toxic mechanism A sensory neuropathy resulting from excessive pyridoxine ingestion, alluded to earlier, is still seen among individuals who take huge doses of vitamin supplements Amitriptyline is capable of producing paresthesias, but the effect seems to be idiosyncratic and infrequent The anesthetic agent trichloroethylene, as with the aforementioned stilbamidine, has a predilection for cranial nerves, particularly the fth The neurotoxicity is apparently due to dichloroacetylene, formed as a decomposition product of trichloroethylene The neuropathic potential of nitrous oxide has already been mentioned.

Rather than using a database as the source for data, the array provides a good simple place to put values to be extracted Then using the LINQ functionality, you can see that while the statements look a lot like SQL statements, they are in fact set up in a standard C# fashion

to estimatethe value at an intermediate nt / (-ri _vi If we use a linear function, re poi the ) sult is a plane connectingthe points as in Fig 169Suchfunctionsare calledbilinear A simple approach developingthe bilinear tunction is depictedin Fig 1610 for First, we can hold the v value fixed and apply one-dimensional lineu interpolation therdiin rectionUsingthe Lagrange form, the resultat (r;, r1) is

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The IEnumerable<T> is a lambda expression With a lambda expression, you can treat code like data A lambda expression works something like an anonymous method where you can place several statements inside the method, but with a lambda, expressions are assigned to the lambda instance as you would assign data Using IEnumerable<T>, all of the LINQ query can be placed in a single assignment It s something like placing a set of SQL commands in a string expression and then executing that expression as using a SqlCommand instance However, instead of SQL, it s LINQ